Top 30 PCI‑Compliant Payment Processors for Healthcare Providers

Curated list of the 30 most reliable, PCI‑DSS‑validated payment processors that support the unique billing, compliance, and patient‑experience needs of medical practices, hospitals, and health‑tech platforms.

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#2 Stripe

Modern API‑first processor with built‑in tokenization, support for ACH, credit cards, and recurring billing; offers a HIPAA‑compatible environment when paired with a compliant host.

#3 Square

All‑in‑one POS and online payment suite; PCI‑Level 1 certified, supports telehealth appointments and integrates with many EMR/EHR systems.

Globally recognized processor with PCI‑DSS compliance, supports credit/debit cards, PayPal Pay‑Later, and secure tokenized transactions for patient portals.

Veteran gateway offering advanced fraud detection, recurring billing, and easy integration with practice management software.

A PayPal service delivering seamless mobile/web checkout, tokenization, and support for multiple currencies—ideal for telehealth platforms.

VMware‑owned solution with robust risk management tools, tokenization, and PCI‑Level 1 compliance; widely used by large health systems.

Enterprise‑grade processor offering integrated clearing, settlement, and reporting; supports complex payer mixes and high‑volume claim payments.

Global payment gateway with PCI‑DSS Level 1 certification, multi‑currency support, and customizable checkout flows for patient billing.

#10 Adyen

Unified commerce platform with end‑to‑end encryption, token vault, and real‑time risk insights; suitable for large hospital networks.

#11 Elavon

Healthcare‑focused gateway offering secure card‑present and card‑not‑present processing, integrated with many EHRs.

#12 Heartland

PCI‑Validated Solution Provider (VSP) delivering tokenization, EMV, and HIPAA‑compatible APIs for medical practices.

#13 TSYS

Comprehensive payment processing suite with advanced fraud tools, recurring billing, and support for health‑care specific reporting.

Enterprise gateway with PCI‑Level 1 compliance, multi‑channel acceptance, and dedicated health‑care integration partners.

#15 BlueSnap

All‑in‑one payment platform offering tokenized checkout, subscription billing, and a PCI‑DSS compliant hosted payment page.

PCI‑Level 1 gateway with transparent pricing, recurring billing, and built‑in ACH processing for patient payments.

#17 PaySimple

Designed for service‑based businesses, it provides secure card processing, automated invoicing, and HIPAA‑ready integrations.

Platform‑as‑a‑service gateway with PCI compliance, easy API integration, and support for marketplace‑style health‑tech apps.

PCI‑DSS Level 1 gateway offering customizable payment forms, tokenization, and batch settlement for clinics.

#20 Payrix

Healthcare‑focused payment processor with built‑in payer‑mix handling, secure token vault, and compliance reporting.

Fiserv‑owned solution delivering tokenization, EMV, and PCI‑Level 1 compliance; integrates with many practice‑management platforms.

#22 PayU

Global gateway with PCI compliance, multi‑currency support, and a robust API for telemedicine platforms operating internationally.

PCI‑DSS certified solution offering hosted checkout, recurring billing, and localized payment methods for patient self‑service portals.

Integrated with QuickBooks accounting; PCI‑Level 1 certified, supports invoicing, ACH, and credit‑card payments for small practices.

UK‑based PCI‑DSS Level 1 gateway offering secure hosted payment pages and API access for international health‑care providers.

#26 Mollie

European payment platform with PCI compliance, supporting SEPA, credit cards, and Apple/Google Pay for cross‑border patient billing.

#27 InstaMed

Specialized health‑care payment network enabling secure electronic payments, payer‑to‑payer transfers, and PCI‑compliant tokenization.

#28 Simplee

Patient‑centric billing platform offering PCI‑Level 1 secure payment processing, payment plans, and integration with major EHRs.

#29 Waystar

Revenue cycle management suite with built‑in PCI‑compliant payment gateway, supporting both online and point‑of‑service collections.

Cloud‑based RCM platform that includes PCI‑validated payment processing for patient statements and self‑service portals.

#31 HealthPay

Dedicated health‑care payment processor offering tokenized card‑on‑file storage, ACH, and compliance reporting for clinics.

Patient‑focused payment solution with PCI‑Level 1 compliance, flexible payment plans, and integration with most practice‑management systems.

Secure gateway built for medical practices, providing tokenization, recurring billing, and detailed compliance logs.

Part of the Kareo practice‑management suite; PCI‑DSS validated, supports online patient portals, and automates insurance‑patient payment splits.

Integrated payment engine with PCI compliance, offering real‑time eligibility checks and automated patient statements.

Cloud‑based billing platform that includes a PCI‑validated payment processor for seamless patient collections.