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#2 Stripe
Modern API‑first processor with built‑in tokenization, support for ACH, credit cards, and recurring billing; offers a HIPAA‑compatible environment when paired with a compliant host.
#3 Square
All‑in‑one POS and online payment suite; PCI‑Level 1 certified, supports telehealth appointments and integrates with many EMR/EHR systems.
Globally recognized processor with PCI‑DSS compliance, supports credit/debit cards, PayPal Pay‑Later, and secure tokenized transactions for patient portals.
Veteran gateway offering advanced fraud detection, recurring billing, and easy integration with practice management software.
#6 Braintree
A PayPal service delivering seamless mobile/web checkout, tokenization, and support for multiple currencies—ideal for telehealth platforms.
#7 CyberSource
VMware‑owned solution with robust risk management tools, tokenization, and PCI‑Level 1 compliance; widely used by large health systems.
Enterprise‑grade processor offering integrated clearing, settlement, and reporting; supports complex payer mixes and high‑volume claim payments.
Global payment gateway with PCI‑DSS Level 1 certification, multi‑currency support, and customizable checkout flows for patient billing.
#10 Adyen
Unified commerce platform with end‑to‑end encryption, token vault, and real‑time risk insights; suitable for large hospital networks.
#11 Elavon
Healthcare‑focused gateway offering secure card‑present and card‑not‑present processing, integrated with many EHRs.
#12 Heartland
PCI‑Validated Solution Provider (VSP) delivering tokenization, EMV, and HIPAA‑compatible APIs for medical practices.
#13 TSYS
Comprehensive payment processing suite with advanced fraud tools, recurring billing, and support for health‑care specific reporting.
#14 Global Payments
Enterprise gateway with PCI‑Level 1 compliance, multi‑channel acceptance, and dedicated health‑care integration partners.
#15 BlueSnap
All‑in‑one payment platform offering tokenized checkout, subscription billing, and a PCI‑DSS compliant hosted payment page.
#16 Payline Data
PCI‑Level 1 gateway with transparent pricing, recurring billing, and built‑in ACH processing for patient payments.
#17 PaySimple
Designed for service‑based businesses, it provides secure card processing, automated invoicing, and HIPAA‑ready integrations.
Platform‑as‑a‑service gateway with PCI compliance, easy API integration, and support for marketplace‑style health‑tech apps.
#19 PayJunction
PCI‑DSS Level 1 gateway offering customizable payment forms, tokenization, and batch settlement for clinics.
#20 Payrix
Healthcare‑focused payment processor with built‑in payer‑mix handling, secure token vault, and compliance reporting.
#21 CardConnect
Fiserv‑owned solution delivering tokenization, EMV, and PCI‑Level 1 compliance; integrates with many practice‑management platforms.
#22 PayU
Global gateway with PCI compliance, multi‑currency support, and a robust API for telemedicine platforms operating internationally.
PCI‑DSS certified solution offering hosted checkout, recurring billing, and localized payment methods for patient self‑service portals.
Integrated with QuickBooks accounting; PCI‑Level 1 certified, supports invoicing, ACH, and credit‑card payments for small practices.
#25 Sage Pay (Opayo)
UK‑based PCI‑DSS Level 1 gateway offering secure hosted payment pages and API access for international health‑care providers.
#26 Mollie
European payment platform with PCI compliance, supporting SEPA, credit cards, and Apple/Google Pay for cross‑border patient billing.
#27 InstaMed
Specialized health‑care payment network enabling secure electronic payments, payer‑to‑payer transfers, and PCI‑compliant tokenization.
#28 Simplee
Patient‑centric billing platform offering PCI‑Level 1 secure payment processing, payment plans, and integration with major EHRs.
#29 Waystar
Revenue cycle management suite with built‑in PCI‑compliant payment gateway, supporting both online and point‑of‑service collections.
Cloud‑based RCM platform that includes PCI‑validated payment processing for patient statements and self‑service portals.
#31 HealthPay
Dedicated health‑care payment processor offering tokenized card‑on‑file storage, ACH, and compliance reporting for clinics.
#32 PatientPay
Patient‑focused payment solution with PCI‑Level 1 compliance, flexible payment plans, and integration with most practice‑management systems.
#33 Medpayment
Secure gateway built for medical practices, providing tokenization, recurring billing, and detailed compliance logs.
#34 Kareo Payments
Part of the Kareo practice‑management suite; PCI‑DSS validated, supports online patient portals, and automates insurance‑patient payment splits.
Integrated payment engine with PCI compliance, offering real‑time eligibility checks and automated patient statements.
Cloud‑based billing platform that includes a PCI‑validated payment processor for seamless patient collections.