Best File Transfer Applications with End-to-End Encryption for Healthcare

HIPAA‑compliant cloud storage and file sharing with TLS‑in‑transit, AES‑256‑at‑rest, and optional end‑to‑end encryption for sensitive health records.

Enterprise‑grade secure file sharing platform offering true end‑to‑end encryption, granular access controls, and full HIPAA Business Associate Agreement (BAA).

Cloud storage with HIPAA BAA, TLS‑in‑transit, AES‑256‑at‑rest; can be paired with third‑party E2EE tools (e.g., Boxcryptor) for full end‑to‑end protection.

Secure content platform that provides HIPAA compliance, TLS/SSL transport, AES‑256‑at‑rest, and optional Box Shield end‑to‑end encryption for PHI.

Google Drive with HIPAA BAA, encrypted in transit (TLS) and at rest (AES‑256); end‑to‑end encryption can be added via third‑party solutions.

Part of Microsoft 365 with HIPAA BAA, TLS/SSL, AES‑256‑at‑rest; integrates with Azure Information Protection for optional end‑to‑end encryption.

Hybrid cloud file‑sharing solution offering HIPAA compliance, TLS/SSL, AES‑256‑at‑rest, and optional end‑to‑end encryption via Egnyte Protect.

Zero‑knowledge cloud storage with built‑in end‑to‑end encryption (AES‑256) and full HIPAA compliance for protected health information.

Swiss‑based secure cloud storage delivering true end‑to‑end encryption, GDPR/HIPAA compliance, and granular permission controls.

Adds client‑side encrypted folders to pCloud storage; uses RSA‑2048 and AES‑256, and offers a HIPAA‑compatible plan for healthcare data.

Zero‑knowledge backup and file sharing service with end‑to‑end encryption (AES‑256) and HIPAA‑ready architecture.

Privacy‑first cloud storage built on end‑to‑end encryption (AES‑256 + RSA‑4096); can be configured for HIPAA‑level protection.

Professional file‑transfer service with password‑protected links, TLS‑in‑transit, and optional client‑side encryption for PHI.

Self‑hosted or cloud file‑sharing platform offering end‑to‑end encryption, granular policies, and full HIPAA compliance.

Enterprise‑grade managed file transfer server with SFTP/FTPS, TLS, and optional end‑to‑end encryption modules for PHI.

Managed file‑transfer solution supporting SFTP, FTPS, HTTPS, and built‑in end‑to‑end encryption to meet HIPAA requirements.

High‑speed secure file transfer platform using FASP protocol, TLS, and optional end‑to‑end encryption for large medical imaging files.

Secure file‑sharing service designed for healthcare, offering true end‑to‑end encryption, audit trails, and HIPAA BAA.

Encryption overlay that adds end‑to‑end protection to existing cloud services (Google Drive, Dropbox, etc.) and supports HIPAA compliance.

Email and file encryption platform delivering end‑to‑end protection, secure links, and full HIPAA coverage.

Secure file‑sharing and collaboration tool with end‑to‑end encryption, detailed audit logs, and HIPAA‑ready environment.

Virtual data‑room and secure file exchange solution offering end‑to‑end encryption, granular permissions, and HIPAA compliance.

Virtual data‑room platform with zero‑knowledge encryption, secure sharing links, and HIPAA‑compatible controls.

Enterprise file‑transfer gateway providing TLS, AES‑256‑at‑rest, and optional end‑to‑end encryption for regulated healthcare data.

Managed SFTP/FTPS server with built‑in end‑to‑end encryption, detailed compliance reporting, and HIPAA‑ready configuration.

Secure FTP service with TLS, AES‑256‑at‑rest, and optional client‑side encryption for transmitting PHI.

Healthcare‑focused integration platform offering secure file exchange with end‑to‑end encryption and full HIPAA compliance.

HIPAA‑compliant email and file transfer service delivering end‑to‑end encryption without the need for passwords or portals.

Specialized healthcare file‑transfer platform offering TLS, AES‑256‑at‑rest, and optional client‑side encryption for PHI.

Encryption layer that adds end‑to‑end encryption to cloud storage services (Box, Dropbox, Google Drive) and supports HIPAA workflows.

Digital asset management system with end‑to‑end encryption options and HIPAA‑compatible data handling for medical images.

Formerly ShareFile; provides secure file sharing with TLS, AES‑256‑at‑rest, and optional end‑to‑end encryption for health data.

Microsoft’s cloud storage combined with Azure Information Protection to deliver true end‑to‑end encryption for PHI.

Standalone secure file‑transfer service offering end‑to‑end encryption, audit trails, and HIPAA BAA.